Chemical probe design

111. Biocatalytic Synthesis of Ribonucleoside Analogues Using Nucleoside Transglycosylase-2

104. A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles

102. Innovative, combinatorial and high-throughput approaches to degrader synthesis

98. Glutathione Mediates Control of Dual Differential Bio-orthogonal Labelling of Biomolecules

97. Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome

96. Fluorous-Directed Assembly of DNA Origami Nanostructures

95. Surface Passivation with a Perfluoroalkane Brush Improves the Precision of Single-Molecule Measurements

94. Oligonucleotide-Recognizing Topoisomerase Inhibitors (OTIs): Precision Gene Editors for Neurodegenerative Diseases?

93. Biophysical characterisation of the Bcl-x pre-mRNA and binding specificity of the ellipticine derivative GQC-05: Implication for alternative splicing regulation

92. Biosynthesis of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis

91. A Chemo- and Regioselective Tandem [3 + 2]Heteroannulation Strategy for Carbazole Synthesis: Combining Two Mechanistically Distinct Bond-Forming Processes

90. Direct, Late-Stage Mono-N-arylation of Pentamidine: Method Development, Mechanistic Insight, and Expedient Access to Novel Antiparastitics against Diamidine-Resistant Parasites

89. A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications

87. Contra-thermodynamic E → Z isomerization of cinnamamides via selective energy transfer catalysis

88. Glasgow Early Treatment Arm Favirpiravir (GETAFIX) for adults with early stage COVID-19: A structured summary of a study protocol for a randomised controlled trial

85. Identification of 2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-N-phenylpropanamides as a novel class of potent DprE1 inhibitors

86. Biocatalytic Alkylation Cascades: Recent Advances and Future Opportunities for Late-Stage Functionalization

84. Two-dimensional infrared spectroscopy: an emerging analytical tool?

62. A Tandem Enzymatic sp2-C-Methylation Process: Coupling in Situ S-Adenosyl-l-Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)

64. Strategy for Conditional Orthogonal Sequential CuAAC Reactions Using a Protected Aromatic Ynamine

63. Ultrafast 2D-IR and optical Kerr effect spectroscopy reveal the impact of duplex melting on the structural dynamics of DNA

61. Reversible DNA micro-patterning using the fluorous effect

60. Determining the Origin of Rate-Independent Chemoselectivity in CuAAC Reactions: An Alkyne-Specific Shift in Rate-Determining Step

59. Transition-Metal-Free Amine Oxidation: A Chemoselective Strategy for the Late-Stage Formation of Lactams

42. An oligofluorene truxene based distributed feedback laser for biosensing applications

34. Directed Assembly of DNA-Functionalized Gold Nanoparticles Using Pyrrole–Imidazole Polyamides

33. Photo-induced growth of DNA-capped silver nanoparticles

30. DNA-Templated Photonic Arrays and Assemblies: Design Principles and Future Opportunities

29. Site-Specific Assembly of DNA-Based Photonic Wires by Using Programmable Polyamides

27. Cu-Catalyzed N-Alkynylation of Imidazoles, Benzimidazoles, Indazoles, and Pyrazoles Using PEG as Solvent Medium

26. Highly Efficient Synthesis of DNA-Binding Hairpin Polyamides via the Use of a New Triphosgene Coupling Strategy

4. New labelling strategies for the sensitive detection of nucleic acids